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4. Aframomum Melegueta Extract (6-Paradol) 20 mg

While the evidence is not as strong as for PPIs, probiotics carry essentially zero risk and may help with multiple GI symptoms simultaneously, including the bloating that often accompanies heartburn

All studies had at least two arms (study medication and placebo)

The result is a 16-amino-acid peptide that stimulates lipolysis (the breakdown of stored fat into usable energy) and inhibits lipogenesis (the creation of new fat cells)

By wrapping the glutathione in this protective fatty layer, the supplement can bypass the destructive acids of the stomach and deliver the antioxidant directly to the cells and bloodstream

Keap1/Nrf2/ARE, p53/SLC7A11 and GSH/GPX4 signaling pathways underlie the pathological mechanism of AD, positioning them as a potential direction for future research